[The structure and function of the mecA gene in methicillin-resistant Staphylococcus aureus].
Copyright policy )[The structure and function of the mecA gene in methicillin-resistant Staphylococcus aureus].
Penicillin binding protein (PBP) 2' is the most important mechanism of the resistance to beta-lactams in methicillin-resistant Staphylococcus aureus (MRSA). And the mecA gene is the coding gene of PBP2', and located in the SmaI fragment G of the chromosome map by Pattle P.A.,. A part of the structure of mecA is similar to that of the penicillinase gene. The resistance of MRSA to beta-lactams were influenced by the presence of penicillinase plasmid and the alternation of femA gene.
Staphylococcus aureus, Lactams, Muramoylpentapeptide Carboxypeptidase, Anti-Bacterial Agents, Bacterial Proteins, Hexosyltransferases, Genes, Bacterial, Multienzyme Complexes, Peptidyl Transferases, Penicillin-Binding Proteins, Methicillin Resistance, Carrier Proteins
Staphylococcus aureus, Lactams, Muramoylpentapeptide Carboxypeptidase, Anti-Bacterial Agents, Bacterial Proteins, Hexosyltransferases, Genes, Bacterial, Multienzyme Complexes, Peptidyl Transferases, Penicillin-Binding Proteins, Methicillin Resistance, Carrier Proteins
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