OBJECTIVE:The color difference between the patient's facial prosthesis and the surrounding skin have long puzzled both of dentist and patient.The purpose of the study was to introduce spectrophotometer into the color matching and set up a set of equations to increase the accuracy of the color matching,Referring to increase the accuracy of the color matching.Referring to color gamut,several sets of shade guide were made according to sixteen kinds of mixture-ratio of four pigments such as red,yellow,white and black,and every shade guide was measured.The mixture-ratio was related to the values of the CIE system by means of statistics,which resulted in the equations for color matching.In a word,use of the spectrophotometer may improve the accuracy of the the color matching of facial prosthesis.