Spectrophotometric determination of diltiazem in dosage forms.

Živanov-Stakić, Dobrila; Agbaba, Danica; Vladimirov, S; Ćirić, L.J

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FarFar - Pharmacy Repository, University of Belgrade

Article . 1992

Data sources: FarFar - Pharmacy Repository, University of Belgrade

Il Farmaco

Article . 1992

Data sources: Europe PubMed Central

Spectrophotometric determination of diltiazem in dosage forms.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1992 Serbia English Journal:Farmaco (Societa chimica italiana : 1989), volume 47 (issn: 0014-827X,

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Authors: Živanov-Stakić, Dobrila; Agbaba, Danica; Vladimirov, S; Ćirić, L.J;

pmid: 1503602

handle: 21.15107/rcub_farfar_97

Spectrophotometric determination of diltiazem in dosage forms.

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Abstract

A simple and reproducible method for determination of diltiazem in bulk and in dosage forms is presented. The method is based on formation of hydroxamic acid, which reacts with iron (III), forming a complex with a maximum absorption at 525 nm. Assay procedure for diltiazem dosage form requires thin-layer chromatographic separation prior to colorimetric analysis.

Country

Serbia

Related Organizations

University of Belgrade
Serbia

Keywords

Diltiazem, Spectrophotometry, Chromatography, Thin Layer, Tablets

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