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[Epidemiology of colorectal cancer liver metastases].

Authors: Jean, Faivre; Sylvain, Manfredi; Anne-Marie, Bouvier;

[Epidemiology of colorectal cancer liver metastases].

Abstract

Hepatic metastases from colorectal cancer represent a serious complication, often at the origin of death. Very few studies allow to know their epidemiological characteristics. From available data the proportion of colorectal cancer with synchronous liver metastases is 15% and the 5 year cumulative risk of metachronous metastases is 16%. According to Côte-d'Or data, it was 4.6% for TNM stage 1 cancer, 14.1% for stage 2 and 32.0% for stage 3. Taking into account incidence and prevalence of colorectal cancer it can be estimated that the number of synchronous hepatic metastases is 5,400 per year and the number of metachronous hepatic metastases 9,000 per year. In the Côte-d'Or area 6.5% of synchronous hepatic metastases, were resected for cure and 21% of metachronous hepatic metastases. The survival rates for synchronous hepatic metastases were 31% at 1 year and 2% at 5 year. The corresponding rates for metachronous metastases were 31% and 4%. After surgery for cure the 5 year survival rate was 11% for synchronous metastases and 16% for metachronous metastases. Population based data indicates that liver metastases from colorectal cancer represent a frequent problem and are more frequent that suggested by hospital-based data.

Keywords

Risk, Carcinoma, Liver Neoplasms, Prevalence, Humans, Antineoplastic Agents, France, Colorectal Neoplasms, Case Management, Neoplasm Staging

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
31
Top 10%
Top 10%
Top 10%
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