Dermal toxicity of paraphenylenediamine.
Copyright policy )Dermal toxicity of paraphenylenediamine.
The guinea pigs were dermally exposed to paraphenylenediamine (PPD) and in presence of an oxidising agent hydrogen peroxide for 15 and 30 d to assess their effects on some enzymes, lipid peroxidation and histamine contents in the skin. The activities of acid and alkaline phosphatases, beta-glucuronidase, gamma glutamyl transpeptidase, histidase and tyrosinase were enhanced after application of either PPD or PPD plus hydrogen peroxide. The lipid peroxidation and histamine contents also showed marked elevation following exposure to the chemicals.
Male, Acid Phosphatase, Guinea Pigs, Hydrogen Peroxide, Phenylenediamines, Alkaline Phosphatase, Drug Combinations, Animals, Lipid Peroxidation, Lysosomes, Glucuronidase, Histamine, Skin
Male, Acid Phosphatase, Guinea Pigs, Hydrogen Peroxide, Phenylenediamines, Alkaline Phosphatase, Drug Combinations, Animals, Lipid Peroxidation, Lysosomes, Glucuronidase, Histamine, Skin
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