[Anemia and recurrences in acute lymphoblastic leukemia in children after the treatment and the frequency of the erythroblasts with micronuclei].
Copyright policy )[Anemia and recurrences in acute lymphoblastic leukemia in children after the treatment and the frequency of the erythroblasts with micronuclei].
A retrospective analysis of the relation of relapses and anaemias to the frequency of micronucleated erythroblasts in bone marrow smear in 140 children with acute lymphoblastic leukaemia after BFM and Memphis schemes of therapy was carried out. The anaemias correlated with the frequency of micronucleated erythroblasts in statistically significant manner. Correlation concerning relapses, was not shown. The frequency of micronucleated erythroblasts in children treated by BFM scheme is lower than by Memphis scheme. This suggests smaller genotoxicity of BFM scheme therapy.
Erythrocytes, Micronucleus Tests, Adolescent, Daunorubicin, beta-Thalassemia, Infant, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Hematopoietic Stem Cells, Bone Marrow, Vincristine, Child, Preschool, Antineoplastic Combined Chemotherapy Protocols, Asparaginase, Humans, Prednisone, Neoplasm Recurrence, Local, Child, Micronuclei, Chromosome-Defective
Erythrocytes, Micronucleus Tests, Adolescent, Daunorubicin, beta-Thalassemia, Infant, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Hematopoietic Stem Cells, Bone Marrow, Vincristine, Child, Preschool, Antineoplastic Combined Chemotherapy Protocols, Asparaginase, Humans, Prednisone, Neoplasm Recurrence, Local, Child, Micronuclei, Chromosome-Defective
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