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[Inactivation of androgens by UDP-glucuronosyltransferases].

Authors: Alain, Bélanger;

[Inactivation of androgens by UDP-glucuronosyltransferases].

Abstract

Liver, kidney, and gastrointestinal tissues are well known to express UDP-glucuronosyltransférase (UGT) enzymes which conjugate exogenous compounds. This mechanism is extremely important to eliminate several compounds from the body. Recent studies have shown that, in addition to the liver and kidney, a large number of tissues, namely the prostate and skin, also express UGT which are capable of inactivating steroids. This mechanism may be a means to modulate the action of steroids in these tissues.

Keywords

Male, Gene Expression Regulation, Liver, Skin Physiological Phenomena, Androgens, Prostate, Humans, Glucuronosyltransferase, Kidney

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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