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Postępy Higieny i Medycyny Doświadczalnej
Article . 2004
Data sources: Europe PubMed Central
Claim

[Notch1 receptor: structure and role during T-cell development].

descriptionPublicationkeyboard_double_arrow_right Article 07 Apr 2004 Polish Journal:Postepy higieny i medycyny doswiadczalnej, volume 57 (issn: 0032-5449, Copyright policy )
Authors: Barbara, Gidzińska;

pmid: 14601249

[Notch1 receptor: structure and role during T-cell development].

Abstract

The Notch family are proteins which function both as cell surface receptors and regulators of gene transcription. Notch proteins influence cell-fate decisions during lymphopoesis, neurogenesis and myogenesis. During lymphopoesis Notch1 is implicated in differentiation of lymphoid precursor CLP towards T-cells bot not B-cells lineage. In spite of earlier results suggesting involvement of Notch1 in commitment towards alpha beta and gamma delta or CD4 and CD8 T cell lineage, later experiments didn't confirm this possibility.

Keywords

Receptors, Notch, T-Lymphocytes, Trans-Activators, Animals, Humans, Membrane Proteins

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold