LEU2 gene homolog in Kluyveromyces lactis.

A DNA fragment that can complement the leu2 mutation of Saccharomyces cerevisiae was cloned from the genomic library of Kluyveromyces lactis. The nucleotide sequence revealed an open reading frame of 362 codons, 75% homologous to S. cerevisiae LEU2 gene. The upstream region contained a CCGGAACCGG sequence identical to the site of leucine-specific control of LEU2. Further upstream, there is a partial open reading frame homologous to rat ribosomal protein L7.

Related Organizations

Fudan University
China (People's Republic of)

Keywords

Kluyveromyces, Open Reading Frames, Base Sequence, Sequence Homology, Nucleic Acid, Genes, Fungal, Molecular Sequence Data, Amino Acid Sequence, DNA, Fungal

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