
The importance of the HLA-gene complex is discussed and, in particular, of the HLA-D locus with respect to the clinical outcome of allografts. The genetic situation is deduced from an evaluation of population and family studies using the mixed lymphocyte culture (MLC). Further methods for the typing of gene products of HLA-D or closely-linked loci are described.
Adult, Histocompatibility Testing, Homozygote, Antigen-Antibody Complex, Antigen-Antibody Reactions, HLA Antigens, Humans, Transplantation, Homologous, Female, Lymphocytes, Lymphocyte Culture Test, Mixed, Child, Alleles
Adult, Histocompatibility Testing, Homozygote, Antigen-Antibody Complex, Antigen-Antibody Reactions, HLA Antigens, Humans, Transplantation, Homologous, Female, Lymphocytes, Lymphocyte Culture Test, Mixed, Child, Alleles
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