[The effect of arginine on hydrolysis of fibrinogen by plasmin and mini-plasmin].

E N, Zolotareva; T V, Grinenko; E V, Skomorovskaia; S A, Kudinov

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Article . 1992

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[The effect of arginine on hydrolysis of fibrinogen by plasmin and mini-plasmin].

descriptionPublicationkeyboard_double_arrow_right Article 06 Oct 1992 Russian Journal:Ukrainskii biokhimicheskii zhurnal (1978), volume 64 (issn: 0201-8470,

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Authors: E N, Zolotareva; T V, Grinenko; E V, Skomorovskaia; S A, Kudinov;

pmid: 1387746

[The effect of arginine on hydrolysis of fibrinogen by plasmin and mini-plasmin].

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Abstract

The rate of plasmin or Val442-plasmin catalyzed hydrolysis of fibrinogen decreases several times as affected by arginine in high concentrations. The enzyme is shown to be not inhibited by arginine. The observed effect is supposed to depend on saturation of the protein-proteins interaction sites located between 442 and 790 amino acid residues.

Keywords

Calorimetry, Differential Scanning, Hydrolysis, Fibrinogen, Peptide Fragments, Kinetics, Spectrometry, Fluorescence, Animals, Humans, Cattle, Electrophoresis, Polyacrylamide Gel, Fibrinolysin

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