Skin virulence of attenuated pseudorabies virus (PRV) strains.
Copyright policy )Skin virulence of attenuated pseudorabies virus (PRV) strains.
After intradermal inoculation of the attenuated pseudorabies virus (PRV) strains, Bartha, MK35 (gI+) and MK35-T-2 (gI-) to rabbits, they caused local inflammatory nodules with oedema reddiness and necrosis. The specifity of these reactions was confirmed by their inhibition with anti-PRV serum. The minimal dose that caused visible skin reaction was about 10(2) TCID50/ml for Bartha and MK35-T-2 (gI-) strains and over 10(4) TCID50/ml for the MK35 (gI+) strain. It is assumed that the established residual skin virulence can serve as an additional distinction marker for attenuated PRV strains.
Sheep, Injections, Intradermal, Virulence, Swine, Guinea Pigs, Vaccines, Attenuated, Herpesvirus 1, Suid, Pseudorabies Vaccines, Animals, Rabbits, Skin
Sheep, Injections, Intradermal, Virulence, Swine, Guinea Pigs, Vaccines, Attenuated, Herpesvirus 1, Suid, Pseudorabies Vaccines, Animals, Rabbits, Skin
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