Ploidy of testicular carcinoma in situ.

Name: Ploidy of testicular carcinoma in situ.
Keywords: Adult, Male, NONSEMINOMA, Ploidies, SEMINOMA, TESTIS, DNA, Neoplasm, Dysgerminoma, GERM-CELL TUMORS, Neoplasms, Germ Cell and Embryonal

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1992 English Publisher:Springer Science and Business Media LLCJournal:Laboratory investigation; a journal of technical methods and pathology, volume 66 (issn: 0023-6837,

Authors: DEGRAAFF, WE; OOSTERHUIS, JW; DEJONG, B; VANPUTTEN, WLJ; CASTEDO, SMMJ; SLEIJFER, DT; KOOPS, HS; +1 Authors

pmid: 1310514

handle: 11370/06cc43e1-cf1f-4378-aafe-e1f06f1507b3

Ploidy of testicular carcinoma in situ.

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Abstract

The ploidy of carcinoma in situ and invasive germ cell tumors of the adult testis was compared by DNA flow cytometry. Irrespective of the tumor type with which it was associated, the median DNA index of carcinoma in situ was about the same as that of seminomas and higher than the DNA index of invasive nonseminomatous germ cell tumors. These data indicate that seminoma and carcinoma in situ cells are not only phenotypically similar but also have the same ploidy.

Related Organizations

University of Groningen
Netherlands

Keywords

Adult, Male, NONSEMINOMA, Ploidies, SEMINOMA, TESTIS, DNA, Neoplasm, Dysgerminoma, GERM-CELL TUMORS, Neoplasms, Germ Cell and Embryonal, Flow Cytometry, GERM CELL TUMORS, Testicular Neoplasms, CYTOMETRY, Humans, PRECURSOR, Carcinoma in Situ

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