Results of treatment of 83 patients with destructive pancreonecrosis were analyzed. Miniinvasive method of transcutaneous introduction of a drain under ultrasonographic control was applied in 16 patients. The method is relatively simple, of a small traumaticity, permits to sanate and to drain purulent cavity quickly. Usage of miniinvasive technologies with low risk for the patient's life and minimal economic expense had permitted to reduce the treatment duration and the frequency of the complications occurrence.