Neurocrine is developing NBI-6024 in collaboration with Taisho, as part of Neurocrine's altered peptide ligand (APL) program, as a potential treatment for type I diabetes. By July 2002, Neurocrine had completed four phase I/II trials of NBI-6024 and the compound was in phase IIb studies in Europe and phase Ib studies in the US. By October 2002, a second phase IIb trial was scheduled to begin in the US later in 2002 or in early 2003.