
The aim of the study was to examine sperm chromosomes from infertile males with teratozoospermia.Basic research studySpermatozoa were obtained from infertile males with teratozoospermia. Intracytoplasmic sperm injection was used to inject human spermatozoa into mouse oocytes in order to examine sperm chromosomes.Chromosomes of spermatozoa obtained from 6 infertile teratozoospermic and 1 fertile normozoospermic males were investigated. The mean frequency of structural chromosome aberrations in amorphous, motile spermatozoa was similar to that of morphologically normal sperm (9 vs. 7.7%). The structural aberrations found in amorphous, immotile spermatozoa reached 93% and revealed severity was significant.Teratozoospermia per se did not increase the frequency of structural chromosome aberrations in sperm. Severe chromosomal damage was revealed when immotile spermatozoa were injected into oocytes by ICSI.
Adult, Chromosome Aberrations, Male, Case-Control Studies, Humans, Oligospermia, Sperm Injections, Intracytoplasmic, Spermatozoa, Infertility, Male
Adult, Chromosome Aberrations, Male, Case-Control Studies, Humans, Oligospermia, Sperm Injections, Intracytoplasmic, Spermatozoa, Infertility, Male
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