
The fungal pathway for L-arabinose catabolism converts L-arabinose to D-xylulose 5-phosphate in five steps. The intermediates are, in this order: L-arabinitol, L-xylulose, xylitol and D-xylulose. Only some of the genes for the corresponding enzymes were known. We have recently identified the two missing genes for L-arabinitol 4-dehydrogenase and L-xylulose reductase and shown that overexpression of all the genes of the pathway in Saccharomyces cerevisiae enables growth on L-arabinose. Under anaerobic conditions ethanol is produced from L-arabinose, but at a very low rate. The reasons for the low rate of L-arabinose fermentation are discussed.
Pentosephosphates, Ethanol, L-Xylulose reductase, Saccharomyces cerevisiae, Arabinose, Fermentation, Pentose fermentation, Anaerobiosis, L-Arabinose, Oxidation-Reduction, L-Arabinitol 4-dehydrogenase
Pentosephosphates, Ethanol, L-Xylulose reductase, Saccharomyces cerevisiae, Arabinose, Fermentation, Pentose fermentation, Anaerobiosis, L-Arabinose, Oxidation-Reduction, L-Arabinitol 4-dehydrogenase
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