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Production of ethanol from L-arabinose by Saccharomyces cerevisiae containing a fungal L-arabinose pathway.

Authors: Richard, Peter; Verho, Ritva; Putkonen, Mikko; Londesborough, John; Penttilä, Merja;

Production of ethanol from L-arabinose by Saccharomyces cerevisiae containing a fungal L-arabinose pathway.

Abstract

The fungal pathway for L-arabinose catabolism converts L-arabinose to D-xylulose 5-phosphate in five steps. The intermediates are, in this order: L-arabinitol, L-xylulose, xylitol and D-xylulose. Only some of the genes for the corresponding enzymes were known. We have recently identified the two missing genes for L-arabinitol 4-dehydrogenase and L-xylulose reductase and shown that overexpression of all the genes of the pathway in Saccharomyces cerevisiae enables growth on L-arabinose. Under anaerobic conditions ethanol is produced from L-arabinose, but at a very low rate. The reasons for the low rate of L-arabinose fermentation are discussed.

Country
Finland
Keywords

Pentosephosphates, Ethanol, L-Xylulose reductase, Saccharomyces cerevisiae, Arabinose, Fermentation, Pentose fermentation, Anaerobiosis, L-Arabinose, Oxidation-Reduction, L-Arabinitol 4-dehydrogenase

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    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
90
Top 10%
Top 10%
Top 10%
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