[Virological and serological surveys for H9N2 subtype of influenza A virus in chickens and men in Shenzhen city].

Xiaowen, Cheng; Jianjun, Liu; Jianfan, He; Fuxiang, Shan

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Article . 2003

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[Virological and serological surveys for H9N2 subtype of influenza A virus in chickens and men in Shenzhen city].

descriptionPublicationkeyboard_double_arrow_right Article 21 Nov 2003Journal:Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, volume 16 (issn: 1003-9279,

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Authors: Xiaowen, Cheng; Jianjun, Liu; Jianfan, He; Fuxiang, Shan;

pmid: 12665894

[Virological and serological surveys for H9N2 subtype of influenza A virus in chickens and men in Shenzhen city].

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Abstract

To understand the distribution of influenza A H9N2 virus in chickens and men in Shenzhen area.Virus isolation was performed in embryonated hen s eggs with routine method. The antibody to H9N2 virus was detected with micro-hemagglutination inhibition (HI) test, then the results were checked by using the neutralization assay in MDCK cells.Totally 27 strains of influenza A H9N2 virus were isolated from chickens in farm markets in Shenzhen, whereas no H9N2 virus was isolated from men. Approximately 26% of human sera with the HI titers > or =20 to H9N2 virus were detected. However only 7% of chicken sera with the HI titers > or =20 to H9N2 virus were detected. Meanwhile the HI titer and (MGT) of antibody to H9N2 virus in human sera increased with age. It was also found that there was a close relationship between HI antibody titer to H9N2 virus in human sera and occupation.The distribution of influenza A H9N2 virus in chicken and men in Shenzhen was rather wide. The human H9N2 virus infection probably derived from chicken H9N2 virus.

Keywords

China, Hemagglutination Inhibition Tests, Antibodies, Viral, Influenza A virus, Seroepidemiologic Studies, Influenza, Human, Influenza A Virus, H9N2 Subtype, Animals, Humans, Chickens

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