
This article reviews the concept of molecular-targeted therapy and the current development status of molecular-targeted agents for lung cancer. Epidermal growth factor receptor inhibitors have shown promising antitumor activity against cisplatin-resistant non-small cell lung cancer in phase II trials. Appropriate clinical evaluation of these agents and collaboration with basic researchers are essential for further development.
Vascular Endothelial Growth Factor A, Lymphokines, Lung Neoplasms, Vascular Endothelial Growth Factors, Antibodies, Monoclonal, Cetuximab, Antineoplastic Agents, Gefitinib, Endothelial Growth Factors, Antibodies, Monoclonal, Humanized, ErbB Receptors, Erlotinib Hydrochloride, Clinical Trials, Phase II as Topic, Drug Delivery Systems, Receptors, Vascular Endothelial Growth Factor, Clinical Trials, Phase III as Topic, Carcinoma, Non-Small-Cell Lung, Quinazolines, Humans, Intercellular Signaling Peptides and Proteins
Vascular Endothelial Growth Factor A, Lymphokines, Lung Neoplasms, Vascular Endothelial Growth Factors, Antibodies, Monoclonal, Cetuximab, Antineoplastic Agents, Gefitinib, Endothelial Growth Factors, Antibodies, Monoclonal, Humanized, ErbB Receptors, Erlotinib Hydrochloride, Clinical Trials, Phase II as Topic, Drug Delivery Systems, Receptors, Vascular Endothelial Growth Factor, Clinical Trials, Phase III as Topic, Carcinoma, Non-Small-Cell Lung, Quinazolines, Humans, Intercellular Signaling Peptides and Proteins
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