A new algorithm for the inflation and deflation timing of the Enhanced External Counterpulsation (EECP) have been developed, A pentium PC and 16 bit microcontroller with parallel interrupt communication were used for developing a new kind of EECP system. The 16 bit microcontroller was used to collect and pre-process the ECG and EECP signals. The pre-processing data is transmitted to PC by the parallel communication interface. According to the new algorithm, PC sent out the sequential control signals and monitor the state of EECP. It is necessary to synchronize the time of aortic valve closure and diastolic augmentation during EECP, under the condition of the patients' safety, the effect of therapy have been extremely improved.