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[Embolization of uterine fibroids].

Authors: S, Murgo; Ph, Simon; J, Golzarian;

[Embolization of uterine fibroids].

Abstract

Uterine artery embolization (UAE) for symptomatic leiomyomas is a new attractive treatment in patients who don't desire pregnancy and for which conventional therapy has failed. Uterine fibroid embolization can also be considered for patients who desire pregnancy when myomectomy is technically difficult or impossible and in case of recurrence after myomectomy. 90% improvements are commonly reported in abnormal bleeding, pelvic pains, and in bulk-related symptoms. Although numerous pregnancies have been reported after UAE, the fertility rate after UAE remains to be compared to myomectomy. Absolute contra-indications are pregnancy, endometrial carcinoma, gynaecologic infections, adnexal masses, and rapid growth of uterine leiomyomas (considered as a significant sign of sarcoma). Besides procedure related risks of angiography some specific complications are reported: deep pelvic vein thrombosis with exceptional pulmonary embolus, vaginal discharges with sometime transcervical expulsion of fibroid (5%), transient or permanent amenorrhea (4-5%) and extensive necrosis (1-2%) with possible perforation and infection. A hysterectomy is needed to manage this complication in 0.9 to 0.3% of case. The mortality rate of embolisation is evaluated to 1/3.000 against 6/10.000 for the hysterectomy. UAE is proposed as a less invasive alternative to hysterectomy and myomectomy for the treatment of symptomatic leiomyomas. This technique allows reducing the hospital stay, the convalescence period, the morbidity and the mortality rate compared to conventional surgical treatment.

Related Organizations
Keywords

Leiomyoma, Contraindications, Patient Selection, Pregnancy Outcome, Length of Stay, Hysterectomy, Embolization, Therapeutic, Treatment Outcome, Pregnancy, Preoperative Care, Uterine Neoplasms, Humans, Female, Morbidity

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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