The aim of the study was the assessment of iodine turnover in healthy pregnant women supplemented by microelement and vitamin preparation Materna.To assess iodine supplementation, a modified PAAM method was used for measurement of iodine concentration in morning urine.50 pregnant healthy women were tested for Materna supplementation. Urine iodine concentration was measured starting from the I trimester of pregnancy and then after 1, 2 and 3 months of Materna administration.It has been found, that 3 months of supplementation with Materna reduces iodine deficiency in 83% of primiparas, while in the same time urine iodine concentration was normal in only 30% of women in their third and next pregnancy.In our opinion iodine urine concentration should be assessed in all multiparas using Materna after 1 month of supplementation in order to correct individual iodine supplementation doses.