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[Conjugated vaccines].

Authors: B, Swennen; J, Sternon;

[Conjugated vaccines].

Abstract

Conjugate vaccines extend the vaccinal prevention for children to more diseases. Conjugating the capsular polysaccharide to a carrier protein transforms a T-independent antigen in a T-dependent, allowing protection of the children (before 2 years of age) against Haemophilus influenzae type b, meningococcal C and pneumococcal infections. This article reviews the 3 conjugate vaccines and their results with focus on some questions: antigens interference in the immunological response, serological subrogate for protection, herd immunity and replacement of circulating serotypes.

Keywords

B-Lymphocytes, Haemophilus Infections, Vaccines, Conjugate, Immunization Programs, T-Lymphocytes, Vaccination, Haemophilus influenzae type b, Child Welfare, Meningococcal Vaccines, Lymphocyte Activation, Pneumococcal Infections, Meningococcal Infections, Pneumococcal Vaccines, Belgium, Child, Preschool, Humans, Child, Haemophilus Vaccines

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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