
Conjugate vaccines extend the vaccinal prevention for children to more diseases. Conjugating the capsular polysaccharide to a carrier protein transforms a T-independent antigen in a T-dependent, allowing protection of the children (before 2 years of age) against Haemophilus influenzae type b, meningococcal C and pneumococcal infections. This article reviews the 3 conjugate vaccines and their results with focus on some questions: antigens interference in the immunological response, serological subrogate for protection, herd immunity and replacement of circulating serotypes.
B-Lymphocytes, Haemophilus Infections, Vaccines, Conjugate, Immunization Programs, T-Lymphocytes, Vaccination, Haemophilus influenzae type b, Child Welfare, Meningococcal Vaccines, Lymphocyte Activation, Pneumococcal Infections, Meningococcal Infections, Pneumococcal Vaccines, Belgium, Child, Preschool, Humans, Child, Haemophilus Vaccines
B-Lymphocytes, Haemophilus Infections, Vaccines, Conjugate, Immunization Programs, T-Lymphocytes, Vaccination, Haemophilus influenzae type b, Child Welfare, Meningococcal Vaccines, Lymphocyte Activation, Pneumococcal Infections, Meningococcal Infections, Pneumococcal Vaccines, Belgium, Child, Preschool, Humans, Child, Haemophilus Vaccines
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