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Local RBC aggregation disturbing blood fluidity and causing stasis in microvessels.

Authors: George, McHedlishvili; Manana, Varazashvili; Leila, Gobejishvili;

Local RBC aggregation disturbing blood fluidity and causing stasis in microvessels.

Abstract

Experiments in rat mesenterium were carried out under conditions when both pressure gradient in the chosen microvessels and their diameters were preserved constant. All details of the hemorheological events were directly visualized and documented by usage of appropriate microscopic video techniques. Intensified RBC aggregation locally produced in individual capillaries, immediately disturbs the normal blood flow structure inside their lumina and deranges the rheological properties of blood flow in the microvessels, which slows down till a full stop. The RBC aggregates gradually grow up due to addition of new cells, which become compressed and appear homogeneous. This usually interferes with restoration of blood flow in capillaries. Further the RBC aggregates can move slowly towards veins, while the flow accelerates immediately as soon as the aggregates reach the larger venules.

Keywords

Erythrocyte Aggregation, Hemostasis, Microcirculation, Hemorheology, Animals, Splanchnic Circulation, Blood Viscosity, Hematologic Diseases, Capillaries, Rats

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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
28
Average
Top 10%
Top 10%
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