The Class II division 2 (Class II/2) malocclusion as originally defined by E.H. Angle is relatively rare. The orthodontic literature does not agree on the skeletal characteristics of this malocclusion. Several researchers claim that it is characterized by an orthognathic facial pattern and that the malocclusion is dentoalveolar per se. Others claim that the Class II/2 malocclusion has unique skeletal and dentoalveolar characteristics. The present study describes the skeletal and dentoalveolar cephalometric characteristics of 50 patients clinically diagnosed as having Class II/2 malocclusion according to Angle's original criteria. The study compares the findings with those of both a control group of 54 subjects with Class II division I (Class II/1) malocclusion and a second control group of 34 subjects with Class I (Class I) malocclusion. The findings demonstrate definite skeletal and dentoalveolar patterns with the following characteristics: (1) the maxilla is orthognathic, (2) the mandible has relatively short and retrognathic parameters, (3) the chin is relatively prominent, (4) the facial pattern is hypodivergent, (5) the upper central incisors are retroclined, and (6) the overbite is deep. The results demonstrate that, in a sagittal direction, the entity of Angle Class II/2 malocclusion might actually be located between the Angle Class I and the Angle Class II/1 malocclusions. with unique vertical skeletal characteristics.