
Ten years after the identification of the gene responsible for fragile X syndrome, recent studies have revealed a list of mRNAs bound by the fragile X gene product and have identified specific sequences required for the interaction between the fragile X protein and its targets. These results are a breakthrough in understanding why absence of the fragile X protein leads to mental retardation.
Binding Sites, Fragile X Messenger Ribonucleoprotein 1, Fragile X Syndrome, Intellectual Disability, Multigene Family, Animals, Humans, Nucleic Acid Conformation, RNA, RNA-Binding Proteins, Nerve Tissue Proteins, RNA, Messenger
Binding Sites, Fragile X Messenger Ribonucleoprotein 1, Fragile X Syndrome, Intellectual Disability, Multigene Family, Animals, Humans, Nucleic Acid Conformation, RNA, RNA-Binding Proteins, Nerve Tissue Proteins, RNA, Messenger
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