Effects of deltamethrin on lipid peroxidation in mice.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2002 Turkey English Publisher:Comparative Toxicology LabJournal:Veterinary and human toxicology, volume 44 (issn: 0145-6296,

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Authors: Bilgili, Ali; Celik, Sefa; Kanbur, Murat; Yarsan, Ender;

pmid: 11931506

handle: 20.500.12483/13975

Effects of deltamethrin on lipid peroxidation in mice.

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Abstract

Effects of deltamethrin on lipid peroxidation were investigated for subacute, subchronic and chronic periods. Deltamethrin was given to Swiss Albino mice at 1.5, 2.5, or 7.5 mg/kg. Lipid peroxidation was evaluated by determining malondialdehyde (MDA) levels in plasma, and determining glutathione peroxidase (GSH-Px), superoxide dismutase (Cu-Zn SOD) and catalase activities in erythrocytes on days 15, 45, and 60. MDA levels increased in deltamethrin dosed groups, especially for the subchronic and chronic periods. GSH-Px, Cu-Zn SOD and catalase activities in erythrocytes were decreased at high doses of deltamethrin, especially at the high dose (7.5 mg/kg) deltamethrin group.

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Turkey

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Keywords

Glutathione Peroxidase, Insecticides, Erythrocytes, Dose-Response Relationship, Drug, Superoxide Dismutase, Pyrethroid Insecticides, Catalase, Mice, Malondialdehyde, Nitriles, Pyrethrins, Animals, Lipid Peroxidation

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