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[Humanized respiratory syncytial virus monoclonal antibody].

Authors: Hiroyuki, Tsutsumi;

[Humanized respiratory syncytial virus monoclonal antibody].

Abstract

Respiratory syncytial virus remains a significant cause of severe lower respiratory tract disease in children. The risk of serious RSV illness is highest among children with prematurity, chronic lung disease and congenital heart disease. No effective vaccine and anti-viral agents have been obtained even now. Therefore, conservative therapy including respiratory aid has been a principal therapy for serious RSV disease. Recently, monthly intramuscular administration of humanized anti-RSV monoclonal antibody(palivizumab) was introduced in clinical fields in USA and Europe. Palivizumab prophylaxis has appeared to be safe and effective for prevention of serious RSV illness in premature children and those with bronchopulmonary dysplasia.

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Keywords

Clinical Trials as Topic, Infant, Newborn, Antibodies, Monoclonal, Infant, Respiratory Syncytial Virus Infections, Antibodies, Monoclonal, Humanized, Antibodies, Viral, Protein Engineering, Respiratory Syncytial Viruses, Mice, Treatment Outcome, Child, Preschool, Animals, Humans, Bronchopulmonary Dysplasia, Palivizumab

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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