
To study sarcomagenesis of the mammary gland and estimate the degree of maturity of its various stages, the author examined 45 postoperative specimens of fibroadenomatosis, fibroadenoma, leaf-shape tumor, sarcoma from the preexisting leaf-shape tumor and stromal sarcoma. Studies on the nucleus-plasma relationship, the mitotic coefficient, frequency and pathology of mitosis and quantitative-qualitative changes in sex chromatin allowed a more reliable estimation of the degree of maturity of cell elements of the fibroblastic origin in the process of malignant transformation.
Cell Transformation, Neoplastic, Sex Chromatin, Humans, Mitosis, Breast Neoplasms, Female, Sarcoma, Adenofibroma
Cell Transformation, Neoplastic, Sex Chromatin, Humans, Mitosis, Breast Neoplasms, Female, Sarcoma, Adenofibroma
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