[Gena types of Shigella enterotoxins of S. flexneri 2a].

S, Bai; X, Li; G, Xia; H, Yuan; W, Zheng; H, Wang

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Article . 2004

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[Gena types of Shigella enterotoxins of S. flexneri 2a].

descriptionPublicationkeyboard_double_arrow_right Article 02 Nov 2004Journal:Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, volume 21 (issn: 0254-6450,

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Authors: S, Bai; X, Li; G, Xia; H, Yuan; W, Zheng; H, Wang;

pmid: 11860800

[Gena types of Shigella enterotoxins of S. flexneri 2a].

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Abstract

To identify homogenous clones of S. flexneri 2a, using gene distribution polymorphism of Shigella enterotoxin 1 (set 1) and Shigella enterotoxin 2 (set 2) in a Shigellosis outbreak caused by S. flexneri 2a.In addition to field epidemiological investigation, 43 strains of S. flexneri 2a were determined by polymerase chain reaction (PCR).The 43 strains (1 from food, 1 from a carrier, 41 from patients) were divided into 3 clones (set1 +/set2 + for 39 strains, set1 -/set2 + for 1, set1 +/set2 - for 3 strains).This outbreak was caused by S. flexneri 2a. The route of transmission was contaminated-food borne. Some sporadic cases were noticed during the outbreak. The method used in this study was satisfactory to the identification of S. flexneri 2a.

Keywords

China, Polymorphism, Genetic, Genotype, Humans, Polymerase Chain Reaction, Disease Outbreaks, Dysentery, Bacillary, Shiga Toxin, Shigella flexneri

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