The use of denture adhesives has been discouraged by the dental profession. The negative attitude toward denture adhesives originates from scientific reports about the irreversible damage of denture bearing tissues caused by the application of denture pads and do-it-yourself liners. This survey of literature shows that, so far, no harmful effects have been reported about powder, cream or liquid denture adhesives. Therefore, it is justifiable to prescribe denture adhesives in some patients in order to improve their denture comfort. Dentists should be proactive in giving patients appropriate information about the different kinds of denture adhesives and in demonstrating their proper use.