[Technetium polyphosphate and technetium diphosphonate. A comparative study].

descriptionPublicationkeyboard_double_arrow_right Article 30 Dec 1975 German Journal:Nuclear-Medizin, volume 14

Authors: W, Henne; H U, Pixberg; P, Pfannenstiel;

pmid: 1178518

[Technetium polyphosphate and technetium diphosphonate. A comparative study].

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Abstract

99mTc-labelled phosphates are the bone seeking agents of choice. The comparison of 99mTc-polyphosphate (Poly-P) and 99mTc-ethane-1-hydroxy-1,1-diphosphonate (EHDP) shows a better in vitro stability of the latter during the first two hours after preparation. The blood clearance of EHDP is superior to Poly-P resulting in reduced background activity at scanning time. Renal excretion over a 4-hour period of urine sampling showed no significant differences between both substances. Blood activity is independent of diuresis.

Keywords

Adult, Male, Time Factors, Technetium, Bone Neoplasms, Breast Neoplasms, Middle Aged, Diuresis, Phosphates, Organophosphorus Compounds, Humans, Female, Bone Diseases, Neoplasm Metastasis, Radionuclide Imaging, Pelvic Neoplasms

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