[Research on the regular pattern of Ag-NOR changes in patients with cancer].

L, Chen; Y, Wan; L, Ding

Found an issue? Give us feedback

https://pubmed.ncbi....arrow_drop_down

https://pubmed.ncbi.nlm.nih.go...

Article . 2002

Data sources: Europe PubMed Central

[Research on the regular pattern of Ag-NOR changes in patients with cancer].

descriptionPublicationkeyboard_double_arrow_right Article 05 Feb 2002Journal:Zhonghua zhong liu za zhi [Chinese journal of oncology], volume 22 (issn: 0253-3766,

Copyright policy )

Authors: L, Chen; Y, Wan; L, Ding;

pmid: 11778278

[Research on the regular pattern of Ag-NOR changes in patients with cancer].

- Summary
- Subjects
- Metrics

Abstract

To correlate the relationship between rDNA transcriptional activity of CD4+ helper T cells and immunity in patients with cancer through silver stainability of nucleolus organizing regions (Ag-NORs).The Th(CD4+) rDNA transcriptional activity was compared among patients with cancer, infectious diseases, non-cancerous non-infectious diseases through image analysis.Th(CD4+) rDNA transcriptional activity was decreased extremely in patients with cancer, but increased in patients with inflammation compared with normal controls.The analysis of Th(CD4+) rDNA transcriptional activity may serve as a new tumor marker for tumor diagnosis and differential diagnosis. Therefore, it may provide an innovative and reliable method for clinical cancer diagnosis.

Related Organizations

Beijing Chao-Yang Hospital
China (People's Republic of)

Keywords

CD4-Positive T-Lymphocytes, Silver Staining, Transcription, Genetic, Neoplasms, Nucleolus Organizer Region, Humans, DNA, Ribosomal

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	0
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average