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http://dx.doi.org/10.1016/S089...
Article
Data sources: CORE (RIOXX-UK Aggregator)
Neuron
Article . 2002
Data sources: Europe PubMed Central
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Claim

Protein phosphatase 1 and LTD: synapses are the architects of depression.

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2002 English Publisher:Cell Press.Journal:Neuron, volume 32 (issn: 0896-6273, Copyright policy )
Authors: Isaac, John;

pmid: 11754828

Protein phosphatase 1 and LTD: synapses are the architects of depression.

Abstract

NMDAR-dependent long-term depression involves the activation of protein phosphatase 1 (PP1) and 2B (calcineurin) and the subsequent dephosphorylation of synaptic proteins. In this issue of Neuron, Morishita et al. (2001) provide evidence that precise targeting of PP1 to synaptic substrates is critical for the expression of LTD.

Related Organizations
Keywords

Protein Phosphatase 1, Long-Term Potentiation, Synapses, Phosphoprotein Phosphatases, Animals, Neural Inhibition

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 20
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
20
Average
Top 10%
Top 10%
Related to Research communities
Neuroscience