Mushroom poisoning does not occur very often but in autumn the incidence increases. The seriousness of symptoms in some cases justifies the revision of this issue just the event of one family cases occurred recently in our environment. In this paper we are presenting two cases of intoxication by Lepiota bruneoincarnata in two patients of the same family who suffers visceral involvement with a hepatic strike down and death in one of the patients. The rarity, and seriousness of symptoms together with the similarity with intoxication by Amanita phalloides seem very interesting to us to be published.