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[Lip-jaw-palate clefts. Heterogenous disease pictures].

Authors: E, Kunstmann; J, Radtke; J T, Epplen;

[Lip-jaw-palate clefts. Heterogenous disease pictures].

Abstract

Orofacial clefts are congenital structural deficits involving the lip with or without the palate. The genetic origins of orofacial clefts have been considered as heterogeneous for a long time. Non-syndromatic clefts are based on complex traits.The different approaches towards the genetics of this multifactorial disease are discussed and the consequences for genetic counselling for patients, persons at risk and their relatives are reflected upon.

Related Organizations
Keywords

Adult, Cleft Palate, Male, Cleft Lip, Chromosome Mapping, Humans, Female, Genetic Predisposition to Disease, Syndrome, Child, Pedigree

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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