[Hereditary cancer: identification, genetic heterogeneity, medico-genetic consult].

R F, Gar'kavtseva; T P, Kazubskaia; L N, Liubchenko; S I, Kozlova; N F, Belev; V Iu, Sel'chuk

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Annals of the Russia...arrow_drop_down

Annals of the Russian academy of medical sciences

Article . 2002

Data sources: Europe PubMed Central

[Hereditary cancer: identification, genetic heterogeneity, medico-genetic consult].

descriptionPublicationkeyboard_double_arrow_right Article 07 Jun 2002 Russian Journal:Vestnik Rossiiskoi akademii meditsinskikh nauk (issn: 0869-6047,

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Authors: R F, Gar'kavtseva; T P, Kazubskaia; L N, Liubchenko; S I, Kozlova; N F, Belev; V Iu, Sel'chuk;

pmid: 11676250

[Hereditary cancer: identification, genetic heterogeneity, medico-genetic consult].

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Abstract

The paper deals with a role of inherited factors responsible for the occurrence of malignant tumors. Inherited types of cancer are shown to occur virtually at its sites and averaged 5-15%. Formalized criteria for identifying inherited cancer diseases and their etiological and genetic heterogeneity are presented. A role of genes that genetically predispose to particular forms of cancer is shown, which allows for early (preclinical) diagnosis and prevention of cancer diseases.

Keywords

Neoplasms, Humans, Genetic Counseling, Genetic Predisposition to Disease

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