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[Experimental protective of fraction I of the plague microbe].

Authors: V N, Pautov; Iu V, Chicherin; V I, Evstigneev; A A, Byvalov; O A, Kedrov;

[Experimental protective of fraction I of the plague microbe].

Abstract

The immunogenic properties of the freeze-dried preparation of fraction I tisolated from the culture of avirulent Pasteurella pestis strain were studied in experiments on hamadryas baboons, guinea-pigs and white mice. The preparation was found to have a pronounced protective effect in hamadryas baboons and white mice, especially when the preparation was used in mixture with incomplete Freund adjuvant. In hamadryas baboons resistance to infection was shown to correlate with hemagglutionation antibody titres.

Keywords

Antigens, Bacterial, Plague, Virulence, Yersinia pestis, Guinea Pigs, Dose-Response Relationship, Immunologic, Haplorhini, Antibodies, Bacterial, Mice, Adjuvants, Immunologic, Bacterial Vaccines, Animals, Papio

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Average
Average
Average
gold