This paper provides an overview of the current research activity at the AstroChemistry Group (ACG) of the Astronomical Observatory of Cagliari (OAC) in the National Institute for Astrophysics (INAF). Our team has been growing up since late ’80s: from our first observations of Diffuse Interstellar Bands (DIBs), several related topics became part of the ACG scientific interests. DIBs’ studies spurred many ideas which were developed during graduate and PhD studies, as the initial observational expertise was expanded to include numerical modelling and laboratory experiments. We here present some highlights of our most recent results.