This is a "General Commentary", dealing, on one side, with a recent review article on Brucella spp. and proposing, on the other side, a pathogenetic mechanism underlying the neurotropic behaviour of Brucella ceti in striped dolphins (Stenella coeruleoalba), with subsequent development of "neurobrucellosis", a disease condition frequently encountered in B. ceti-infected individuals of the aforementioned species.