A marine sequence from Central Adriatic Sea (Meson-Adriatic Depression) was analyzed by means of paleomagnetic/rock magnetic analysis then integrated with micropaleontological data (planktonic foraminifera) and AMS14C measurements. The core chronology of the late 3000 years was mostly based on the correlation of paleomagnetic inclinations with those of the UK master curve and supported by radiometric data. The chronology of the lower portion of the core was based on the occurrence of the sapropel S1 (clearly indicated by the concentration magnetic parameters) and of the planktonic foraminifera Globorotalia inflata. Magnetic parameters vary within the range that fulfill the criteria for a relative geomagnetic paleointensity (RPI) study. RPI record was obtained by normalizing the intensity of natural remanent magnetization (NRM20mT) by anhysteretic remanent magnetization (ARM20mT). The last 7000 years of the record is in good agreement with (a) the paleointensity record reconstructed by the geomagnetic global model CALS10k.1b (Korte et al., 2011), (b) with the regional models for Europe SCHA.DIF.3k (Pavón-Carrasco et al., 2009) and SCHA. DIF.8K (Pavón-Carrasco et al., 2010). In addition, our record agrees with relative paleointensities from MAD in central Adriatic Sea (new record computed using data from Vigliotti et al., 2008) and Augusta Bay in Sicily (Sagnotti et al., 2011).