There are two approaches toward dealing with systemic sclerosis (scleroderma) presenting with no skin involvement. According to one of these the condition is to be treated as atypical systemic sclerosis (scleroderma). With the other approach it does not make much difference whether systemic sclerosis presents with skin involvement or not. In the study made a group of systemic sclerosis patients presenting with no skin involvement was examined vs patients with circumscribed skin involvement. No evidence has been found for systemic sclerosis (scleroderma) sine scleroderma to be regarded as running an atypical course.