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Bilecik Şeyh Edebali University Institutional Repository
Review . 2018
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PNP (Purine Nucleoside Phosphorylase)

descriptionPublicationkeyboard_double_arrow_right Review 01 Jan 2018 Turkey English Publisher:Atlas of genetics and cytogenetics in oncology and haematology
Authors: Gurbanov, Rafig; Tunçer, Sinem;

handle: 11552/6614

PNP (Purine Nucleoside Phosphorylase)

Abstract

The purine nucleoside phosphorylase gene (PNP) encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. PNP is ubiquitously expressed in mammalian cells and tissues. PNP mutations cause nucleoside phosphorylase deficiency which result in defective T cell mediated immunity but can also affect B cell immunity and antibody responses.

Country
Turkey
Related Organizations
Keywords

PNP deficiency, Purine metabolism, Immunodeficiency, Purine nucleotide phosphorylase (PNP), Cancer

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    popularity
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    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
Related to Research communities
Cancer Research