Erythrocyte deformation in simulated weightless human and rabbits.
Copyright policy )Erythrocyte deformation in simulated weightless human and rabbits.
Effect and mechanism of simulated weightlessness (SWL) in humans and rabbits erythrocyte deformation were studied. Erythrocyte deformation and membrane fluidity in humans and rabbits, and erythrocyte morphology and hemorreology indices in control and HDT rabbits were measured. The results were a decrease in erythrocyte deformation and membrane fluidity in humans and rabbits during SWL, a significant increase in abnormal erythrocyte, blood viscosity, hematocrit, fibrinogen, and red blood cell aggregation index in HDT rabbits. These results show that the changes in erythrocyte shape, increase of erythrocyte internal viscosity and changes in erythrocyte visco-elasticity may be causing the decrease of erythrocyte deformation in SWL humans and rabbits.
Adult, Male, Adolescent, Membrane Fluidity, Microcirculation, Erythrocyte Membrane, Erythrocytes, Abnormal, Blood Physiological Phenomena, Head-Down Tilt, Erythrocyte Deformability, Hemorheology, Animals, Humans, Rabbits, Bed Rest, Weightlessness Simulation
Adult, Male, Adolescent, Membrane Fluidity, Microcirculation, Erythrocyte Membrane, Erythrocytes, Abnormal, Blood Physiological Phenomena, Head-Down Tilt, Erythrocyte Deformability, Hemorheology, Animals, Humans, Rabbits, Bed Rest, Weightlessness Simulation
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