Novelty: A bioactive coating is formed on a biomedical implant by contacting the surface(s) of the medical implant prior to implantation with a plasma gas containing a reactive hydroxylating oxidant. Use: For modifying surface(s) of metallic biomedical implants such as artificial bone, joints, tooth roots, knee joints, elbows, knuckles, hips, cranio facial screws and orthopedic screws, to accelerate or improve in situ fixation of implant to bone. Advantage: The method improves performance, mechanical strength and adhesion of implant, induces calcium hydroxy phosphate nucleation and promotes bone regrowth and attachment to the surface. The method enables formation of thin coating on implant structures without affecting the surface structure of the implant.