Regional flood frequency techniques are commonly used to estimate flood quantiles when flood data are unavailable or the record length at an individual gauging station is insufficient for reliable analyses. These methods compensate for limited or unavailable data by pooling data from nearby gauged sites. This requires the delineation of hydrologically homogeneous regions in which the flood regime is sufficiently similar to allow the spatial transfer of information. Therefore, several Regional Flood Frequency Analysis (RFFA) methods are applied to the Ceyhan Basin. Dalyrmple (1960) Method is applied as a common RFFA method used in Turkey. Multivariate statistical techniques which are Stepwise and Nonlinear Regression Analysis are also applied to flood statistics and basin characteristics for gauging stations. Rainfall, Perimeter, Length of Main River, Circularity, Relative Relief, Basin Relief, Hmax, Hmin, Hmean and HΔ are the simple additional basin characteristics. Moreover, before the analysis started, stations are clustered according to their basin characteristics by using the combination of Ward’s and k-means clustering techniques. At the end of the study, the results are compared considering the Root Mean Squared Errors, Nash-Sutcliffe Efficiency Index and % difference of results. Using additional basin characteristics and making an analysis with multivariate statistical techniques have positive effect for getting accurate results compared to Dalyrmple (1960) Method in Ceyhan Basin. Clustered region data give more accurate results than non-clustered region data. Comparison between clustered region and non-clustered region Q100/Q2.33 reduced variate values for whole region is 3.53, for cluster-2 it is 3.43 and for cluster-3 it is 3.65. This show that clustering has positive effect in the results. Nonlinear Regression Analysis with three clusters give less errors which are 29.54 RMSE and 0.735 Nash-Sutcliffe Index, when compared to other methods in Ceyhan Basin.