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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
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Kanser biyokimyası

Authors: Yokuş, Beran; Çakır, Dilek Ülker;

Kanser biyokimyası

Abstract

In consequences of recent researches, new approaches had been presented for cancer and biochemical mechanisms explaning every steps of cancer from formation to maturation. Cancer is multistep and long term process at genotypical and phenotypical level. The formation and maturation of cancer are tried to explain in molecular level by biochemical mechanisms responsible from cell seperation and development molecules stimulating cell development, proteins controlling and arranging development genes and mechanisms responsible to limit development just in time.İn the future, the new and more special treatment methods are necessary instead of classical cancer treatments owing to new knowledgements obtained on the cell cycle and cancer field.

Son yıllarda yapılan çalışmalar kanserin oluşumu ve gelişimi ile ilgili biyokimyasal ve moleküler düzeyde yeni katkılar sağlamıştır. Kanser çok basamaklı ve uzun süreli genotipik ve fenotipik düzeyde bir süreçtir. Günümüzde hücre bölünme ve büyümesinden sorumlu biyokimyasal mekanizmalar, hücre büyümesini uyaran moleküller, büyüme mekanizmasını kontrol eden proteinler, gerektiği zamanda büyümenin sınırlandırılmasından sorumlu olan genler ve mekanizmalar ile kanser oluşumu ve gelişimi, moleküler düzeyde açıklanmaya çalışılmaktadır. Önümüzdeki yıllarda, klasik kanser tedavileri yerine hücre siklusu ve kanser alanında elde edilen yeni bilgilerin ışığında, yeni ve daha özel tedavi yöntemleri uygulanacaktır.

Country
Turkey
Related Organizations
Keywords

ROS: Reaktif oksijen türü, Kanser biyokimyası, PTK: Protein trozin kinaz, GAP: GTPaz aktive edici protein, pRB: Retinoblastoma proteini, GTP: Guanozin tri fosfat, DNA onarım genleri, Sitokinler, JAK: Januz kinaz, Apopitozis, Hücre siklusu, Onkogenez, Kanser, PDGF: Plateletten türeyen büyüme faktörü, TGF: Dönüştürücü büyüme faktörü, Tümör baskılayıcı genler, Onkogenler, Hücre büyümesi, GDP: Guanozin di fosfat, CDK: Siklin bağımlı kinaz, Protoonkogenler, MPF: Maturasyon promoting faktör

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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