The purpose of this study is to investigate whether the personal accomplishment of the sales department employees working in pharmaceutical industry is affected by emotional exhaustion and depersonalization or not. Based on the internal dynamics of burnout syndrome, the mechanism that builds personal accomplishment feeling of employees is the research question of this study. In the extant literature, the relationship among the internal dimensions of burnout has not attained a consensus. This research provides an important contribution to the existing literature by explaining the statistically significant relationships among personal accomplishment, emotional exhaustion and depersonalization. This research is a quantitative study. Research data were gathered from the sales employees working at pharmaceutical companies, by means of a questionnaire. All of the items are collected on a Likert-type 5-level measurement tool. Test of hypotheses was performed by means of partial least square structural equation modeling (PLS-SEM) method. The findings designate a negative and significant relationship between emotional exhaustion and personal accomplishment, and between depersonalization and personal accomplishment. In conclusion, this study recommends some practical managerial implications to increase the personal accomplishment feeling of employees.