Inadequate intake of zinc (Zn) by humans can lead to hidden health problems, especially in women and children of poorer regions with a high risk of malnutrition. Therefore, the enrichment of Zn in edible plant tissues through Zn fertilization is considered an effective approach in this regard. This study aims to investigate the biological enrichment of Zn in some of the microgreens belonging to the Brassicaceae family, and to evaluate their Zn uptake potential. Cauliflower, broccoli, and cabbage microgreens grown with the addition of different doses of ZnSO4 (0, 5, 10, 20 mg kg(-1)) in the nutrient solution were analyzed for their fresh and dry weights, as well as the nutrient element content (P, K, Ca, Mg, Fe, Mn, Zn, and Cu). The results show that enhanced Zn levels affect the varieties differently; therefore, the response to Zn enrichment was genotype-specific. The highest fresh weight (13.89 g) was determined in broccoli mi- crogreens at 10 mg kg(-1) Zn application, while the lowest (5.87 g) was found in cauliflower micro- greens at the control treatment (Zn0). The highest Zn content was determined in cauliflower, broccoli, and cabbage microgreens treated with 20 mg kg(-1) Zn. The application of 5 mg kg(-1) Zn significantly affected the Ca, Mg, and Mn content of cabbage microgreens. The biological enrich- ment of Zn in cauliflower, broccoli, and cabbage microgreens from the Brassicaceae family is expected to have positive effects on human health and can be considered as an option, particularly for counteracting Zn deficiency.