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Apoptose em otorrinolaringologia e cabeça e pescoço

Authors: Drimel Molina, Fernando; Golloni-Bertollo, Eny Maria; Taboga, Sebastião Roberto; Maniglia, José Victor;

Apoptose em otorrinolaringologia e cabeça e pescoço

Abstract

This paper intend to review recent advances in our understanding of programmed cell death, or apoptosis, and discuss implications of these basic science advances in the development of causes and potential treatments of a variety of diseases of the head and neck. Conclusions: apoptosis is now understood to be important in the normal development and survival of all multicellular organism. Deregulation of this normally tighly controlled process underlies a variety of disease states, including neoplasia, autoimmune disease, and disorders of the central nervous system. A better understanding of this process and regulation may help otolaryngologists better understand diseases relevant to this specialty and will lead to improved therapeutic interventions.

Country
Brazil
Keywords

protein p53, otorhinolaryngology, protein bcl x, Apoptosis, olfactory nerve disease, systemic lupus erythematosus, virus infection, Adenovirus, Cancer, protein bcl xl, medical specialist, apoptosis, protein function, Parkinson disease, ovary tumor, breast adenoma, cell activity, Poxvirus, prostate carcinoma, Alzheimer disease, liver disease, carcinogenesis, protein Bax, protein bcl 2, aplastic anemia, review, autoimmune disease, ischemia, cell survival, Programed cell death, protein BAD, vestibular disorder, follicular lymphoma, Herpes virus, Poxvirus infection, human, Head and neck tumors, nonhuman, hormone dependence, Fas antigen, central nervous system, molecular dynamics, Otorhinolaringology, cell proliferation, protein analysis, cell function, Herpes virus infection, protein determination, glomerulonephritis, neoplasm, cell structure

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
Related to Research communities
Cancer Research